North Carolina Law Review

University of North Carolina School of Law

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Chapel Hill, NC 27514

97 N.C. L. REV. 1497 (2019)

Concerns over patent protection covering new forms of gene editing have largely focused on the intellectual property covering the editing mechanism itself, most notably CRISPR (clustered regularly interspaced short palindromic repeats), but a...

97 N.C. L. REV. 1463 (2019)

Long overpromised and underdelivered, gene therapy has at last achieved clinical validation and, with the advent of improved gene-editing technologies such as CRISPR, seems poised to play a rapidly expanding role in medical care. However, som...

97 N.C. L. REV. 1399 (2019)

Although scientists have been manipulating genomes since the 1970s, the recent discovery of Clustered Regularly Interspaced Short Palindromic Repeats (“CRISPR”) has expanded the possibilities not only for what gene editing might accomplish bu...

97 N.C. L. REV. 1359 (2019)

Gene-environment interactions play a key role in how psychiatric disorders manifest and develop. Psychiatric genetics researchers are making progress in identifying genomic correlates of many disorders. And recently, the field of genetics has...

July 4, 2019

97 N.C. L. REV. 1329 (2019)

CRISPR-Cas9 genome-editing technology (“CRISPR”) offers a potential solution for some of the world’s critical conservation challenges. Scientists are harnessing CRISPR to expand genetic diversity of endangered species, control invasive specie...

97 N.C. L. REV. 1273 (2019)

The development of accelerated gene-editing techniques, including clustered regularly interspaced short palindromic repeats (CRISPR), carries ethical, legal, and social implications for agriculture. There are some in the genomic sciences who...

97 N.C. L. REV. 1241 (2019)

Since William Bateson’s 1906 coinage of the term “genetics,” the rise of mice as a model organism for biomedical research has gone hand in hand with genomic developments. In today’s research environment, mice and rats make up the vast majorit...

July 4, 2019

97 N.C. L. REV. 1147 (2019)

Genetically modified humans are among us. Emerging technologies for genome editing have launched humanity into the uncharted territory of modifying the human germline—namely, the reproductive cells and embryos that carry our genetic ancestry....

97 N.C. L. REV. 1093 (2019)

Genome-editing technologies promise novel therapies for hematologic disorders. Sickle cell disease (“SCD”), the most common inherited blood disorder, has been identified as one condition where somatic genome editing may provide a cure to alle...

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